Pullman

$7.5M to study if kratom helps Coug sufferers of chronic pain

Seventy-five million dollars.

3 min readResearch
$7.5M to study if kratom helps Coug sufferers of chronic pain

Seven and a half million dollars to study whether a controversial tree leaf can help people who hurt every day. That's the kind of bet that makes you proud to be a Coug, and it's the kind of science that matters more than any scoreboard. While we were all watching Coach Citowicki on the Texas State loss and what's next for Cougar Soccer and wondering if Eshelman looks sharp but Cougs still chasing the Pac-12 pack, a team in Pullman quietly started work that could touch more lives than any single season ever will. This is the WSU we actually talk about over beers at the Coug: the one that goes after the hard, messy, underfunded questions nobody else wants to touch.

Kratom is a mess. It's not FDA-approved. It's banned in several states and cities. The FDA itself warns against it. At low doses it acts like a stimulant; at high doses, like an opioid. It carries real risks of addiction and overdose. But here's the thing Mary Paine, the WSU professor leading the project, said plainly: decisions are being made without concrete scientific evidence. That's not a defense of kratom. It's a defense of knowing what you're talking about before you regulate or dismiss something that 60 million Americans might already be trying on their own. The NIH grant puts WSU in the middle of that argument, and that's exactly where a land-grant university should be.

The study itself is smartly built. Natural products chemists at UNC Greensboro will authenticate a pure form of the botanical, stripping out the mystery additives you'd find in a gas station tincture. Researchers at Arizona and WSU will run mouse models. Then Paine's group, along with the WSU Sleep and Performance Center, will run a human sleep study on people with chronic low back pain. That's a real, everyday kind of pain, not a lab curiosity. The interdisciplinary team spans three WSU colleges and two other universities. It's a five-year project, and it's designed to produce the kind of data needed to design full-scale clinical trials. In other words, they're not rushing to say yes or no. They're building the case to say either one with confidence.

Here's the take you can text a friend: WSU is doing the work that might actually give people a choice. If kratom turns out to be dangerous in ways we can finally prove, that's useful. If it turns out to help people with chronic pain sleep better and live better, that's even more useful. Either way, we'll know because Pullman did the science. And if you need a reminder of how rare that is, consider that a Freeman grad named Boen Phelps just broke a Coug heart in Boise, another story of talent leaving the Palouse. This one stays. Go Cougs.

From Research

PULLMAN, Wash. — Could the botanical known as kratom safely help millions of people worldwide who suffer with chronic pain?

Researchers at Washington State University will lead a team pursuing an answer over the next five years, funded by a $7.5 million grant from the National Institutes of Health. Although kratom is widely marketed as a pain reliever and alternative to opioids, relatively little is known about its effects on human health. The project will investigate how kratom works, its risks, and its impact on sleep and quality of life for those suffering from chronic pain.

Read the original at Research

Briefing

Source
Research
Published
October 26, 2026