Schizophrenia

WSU study links gene deletions to tougher cognitive symptoms in schizophrenia

There's something quietly powerful about a study that digs into why some people face harder battles than others.

4 min readUW News
WSU study links gene deletions to tougher cognitive symptoms in schizophrenia
Researchers at the University of Washington are investigating how genetic changes impact the severity of schizophrenia symptoms. How schizophrenia manifests — and how severely — differs between patients. Photo: Pixabay
From UW News

Schizophrenia affects approximately 23 million people worldwide, with onset usually occurring during a person’s late adolescence to their 20s. Impairments associated with schizophrenia include hallucinations, delusions and disorganized thinking and behavior.

Now, researchers at the University of Washington are investigating how genetic changes impact the severity of schizophrenia symptoms. A new study, published in the American Journal of Psychiatry, supports the idea that deletions in genes that regulate early brain and neuron development are associated with more severe features of schizophrenia spectrum disorders, particularly lower cognitive abilities.

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