First time in Argentina, stick to Buenos Aires or take overnight trips?

Heading to Buenos Aires (and South America in general) for roughly 10 days next month.

Two gringos in their 30s, largely focused on good food, good wine, and hitting up a few museums.

Very torn between the idea of leisurely exploring Buenos Aires, maybe a day in Tigre or Colonia, or taking any of these trips:

- Iguazu

- Mendoza

- Bariloche

- Ushuaia

I realize the weather in Bariloche or Ushuaia would obviously not be warm and sunny, but have always been a big fan of dramatic mountain landscapes.

Any recommendations for any of these, or whether sticking to BA would be better?